In addition, 16.9 (370/2192) and 71.7% (1572/2192) of the isolates were of non-wild-type phenotype to itraconazole and posaconazole, respectively. Overall, 22.2% (823/3702) of the isolates were resistant to fluconazole, with 90.4% (744/823) being cross-resistant to voriconazole. Antifungal susceptibility was determined by Clinical and Laboratory Standards Institute disk diffusion (CHIF-NET10-14, n = 1510) or Sensititre YeastOne (CHIF-NET15-18, n = 2192) methods. Species identification was carried out by mass spectrometry or rDNA sequencing. tropicalis isolates ( n = 3702) were collected from 87 hospitals across China. tropicalis causing invasive candidiasis in China, from a 9-year surveillance study.įrom August 2009 to July 2018, C. Here we report on the epidemiology and antifungal susceptibility of C. There have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. 12 Medical Laboratory Center, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, China.11 Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.10 Department of Laboratory Medicine, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.9 Department of Clinical Laboratory, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.8 Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.

7 Department of Clinical Laboratory, Jiangsu Province Hospital, Nanjing, Jiangsu, China.6 New South Wales Health Pathology, Regional and Rural, Orange Hospital, Orange, NSW, Australia.5 School of Biomedical Sciences, Charles Sturt University, Orange, NSW, Australia.4 Department of Infectious Diseases and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.3 State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.2 Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.1 Department of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.Zi-Yong Sun, Zhong-Jv Chen, Ying-Chun Xu, Meng Xiao, Mei Kang, Yu-Ling Xiao, Ya-Ning Mei, Fang Ni, Yu-Hong Pan, Lan-Mei Gao, Hui Xu, Hui Xu, Kang Liao, Peng-Hao Guo, Hai-Shen Kong, Qing Yang, Wei-Ping Wang, Yan-Ping Luo, Li-Yan Ye, Hua Yu, Lin Yin, Da-Wen Guo, Lan-Ying Cui, Peng-Peng Liu, Hong He, Yan Jin, Hui Fan, Yun-Song Yu, Jie Lin, Ruo-Yu Li, Zhe Wan, Ling Ma, Shuai-Xian Du, Wen-En Liu, Yan-Ming Li, Tie-Li Zhou, Qing Wu, Xin-Lan Hu, Ning Li, Rong Zhang, Hong-Wei Zhou, Yi-Min Li, Dan-Hong Su, Qiang-Qiang Zhang, Li Li, Yun Xia, Li Yan, Zhi-Dong Hu, Na Yue, Yan Jiang, Zhi-Yong Liu, Yu-Ting Zheng, Wei Cao, Yun-Zhuo Chu, Fu-Shun Li, Yun Liu, Yuan-Hong Xu, Ying Huang, Wei Jia, Gang Li, Huo-Xiang Lv, Qing-Feng Hu, Xiu-Li Xu, Xiao-Yan Chen, Xiao-Ling Ma, Huai-Wei Lu, Yin-Mei Yang, Hui-Ling Chen, Jian-Sheng Huang, Hui Jing, Bin San, Yan Du, Hong-Jie Liang, Bin Yang, Yu-Lan Lin, Shan-Mei Wang, Qiong Ma, Hong-Mei Zhao, Li-Wen Liu, Qing Zhang, Fei Xia, Jin-Ying Wu, Mao-Li Yi, Xiang-Yang Chen, Wei-Ping Lu, Xiao-Yan Zeng, Jing Zhang, Jing Wang, Xiao-Guang Xiao, Jia-Yin Liang, Fan-Hua Huang, Gui-Ling Zou, Xue-Fei Du, Xiao-Ming Wang, Xu-Feng Ji, Yong Liu, Zhi-Jie Zhang, Yu-Xing Ni, Sheng-Yuan Zhao, Xiu-Lan Song, Chun-Yan Xu, Chun-Yan Xu, Lin Meng, Xian-Feng Zhang, Jian-Hong Zhao, Hong-Lian Wei, Xue-Song Xu, Weil Li, Yu-Ping Wang, Mei Xu, Yun-Duo Wang, Jing Song, Tian-Pen Cui, Zhi-Min Hu, Ting-Yin Zhou, Hai-Qing Hu, Xiao-Min Xu, Shan-Yan Liang, Lin-Qiang Deng, Hui Chen, Xiao-Jun Sun, Hai-Bin Wang, Jian-Bang Kang, Tie-Ying Hou, Ping Ji, Na Chen, Wen-Jun Sui, Hai-Tong Gu, Xiao-Qin Ha, Yuan-Yuan Zhang, Shu-Feng Wang, Hong Lu, Yi-Hai Gu, Xuan Hou, Rong Tang, Yan-Yan Guo, Fei Huang, Long-Hua Hu, Xiao-Yan Hu, Juan Li, Lian-Hua Wei, Dan Liu, Yan-Qiu Han, Yi-Hui Yao, Jian-Sheng Wang, Jie Wang, Wei Li, Li-Ping Ning, Wei-Qing Song, Yu-Jie Wang, Liang Luan

Ni de yan lei jiu shi liang jing jing